Physicochemical properties of phenobarbital solid dispersion with phosphatidylcholine.
نویسندگان
چکیده
منابع مشابه
Investigation of Solid Dispersion Technique in Improvement of Physicochemical Characteristics of Ibuprofen Powder
Ibuprofen solid dispersions were prepared by the solvent and fusion-solvent methods using polyethylene glycol (PEG), polyvinylpyrrolidone (PVP), eudragit RS PO, eudragit RL PO and hydroxypropylmethylcellulose (HPMC) as carriers to improve physicochemical characteristics of ibuprofen. The prepared solid dispersions were evaluated for the flowability, solubility characteristics and dissoluti...
متن کاملPhysicochemical characterization of solid dispersion systems of tadalafil with poloxamer 407 VIKRANT VYAS
the treatment of erectile dysfunction (1). It is a selective, potent and reversible competitive inhibitor of the enzyme phosphodiesterase-5 (PDE5), which causes inactivation of cyclic guanosine monophosphate (cGMP) (2). Due to longer duration of its action (approximately 36 hours) and minimum potential to cause vision abnormalities, tadalafil has gained wide clinical acceptance. However, it has...
متن کاملPhysicochemical characterization of solid dispersion systems of tadalafil with poloxamer 407.
Dissolution behaviour of a poorly water-soluble drug, tadalafil, from its solid dispersion systems with poloxamer 407 has been investigated. Solid dispersion systems of tadalafil were prepared with poloxamer 407 in 1:0.5, 1:1.5 and 1:2.5 ratios using the melting method. Characterization of binary systems with FTIR and XRPD studies demonstrated the presence of strong hydrogen bonding interaction...
متن کاملInvestigation of Solid Dispersion Technique in Improvement of Physicochemical Characteristics of Ibuprofen Powder
Ibuprofen solid dispersions were prepared by the solvent and fusion-solvent methods using polyethylene glycol (PEG), polyvinylpyrrolidone (PVP), eudragit RS PO, eudragit RL PO and hydroxypropylmethylcellulose (HPMC) as carriers to improve physicochemical characteristics of ibuprofen. The prepared solid dispersions were evaluated for the flowability, solubility characteristics and dissolution be...
متن کاملinvestigation of solid dispersion technique in improvement of physicochemical characteristics of ibuprofen powder
ibuprofen solid dispersions were prepared by the solvent and fusion-solvent methods using polyethylene glycol (peg), polyvinylpyrrolidone (pvp), eudragit rs po, eudragit rl po and hydroxypropylmethylcellulose (hpmc) as carriers to improve physicochemical characteristics of ibuprofen. the prepared solid dispersions were evaluated for the flowability, solubility characteristics and dissolution be...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1990
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.38.2237